You are viewing a Navigating Care library resource. Adriamycin (also known as The Red Devil) is the tough chemo that people hear about. It would ease up by Wednesday, in time to do it all over again. Often I want to (and sometimes do) scream from outrage at this assault upon my body and my life . I followed her advise and helped me a lot. Several doctors suggested the cause of the “seizures” may have been low blood sugar or low blood pressure. Best of Luck to everyone out there going through this. and plainly feel like crap. Your user session will expire in 2 minutes. The whole time I’m taking double doses of omemprozole, pepcid ac and zantac just to try and get it under control so I can eat and drink regularly. Hi everybody, People were going to be amazed by my resolve and inspiration to others. Still have the odd sour cream – I want some enjoyment from food. Doxorubucin belongs to a class of compounds known as anthracyclines, which were originally extracted from Streptomyces bacteria. Ok, I feel better….it helps to vent to people who can understand and not just think I’m whining! Uses: Taxol usually is given in combination with other chemotherapy medicines and is used after surgery to: reduce the risk of early-stage breast cancer coming back; treat advanced-stage breast … Ginger tea (which you can find at World Market) sweetened with a touch of honey is a great natural way of keeping nausea under control. We immediately tested my blood sugar and it was very low: 53, so we took counter measures. Last time only 8 treatments and I kept my hair. I believe they go by statistics – just whose I am not sure???? Bewy 22 that result sounds spectacular! So the doctor gave me a 2 week break. I’d rather do that than feel sick. With my AC treatments I only got sick at my stomach with the first 2 but it was no where near as bad as I thought it would be. It has been a great source of information and support. and a minimum of easy-to-absorb starches. Chemotherapy is life-saving medicine, no doubt, but it can take a severe toll on your life in the meantime. The first 4 treatments was the ‘Red Devil’ every other week, then they tried Traxol. I have been able to soothe my stomach with black tea, ginger ale or Kefir (liquid yogurt), also by trying to calm myself down, and standing up and walking around…. Sometimes I wish I’d never found my lump (diagnostic mammo couldn’t either!) My oncologist and associated doctors (surgeon and radiation oncologist) have agreed that I’ve been fortunate with side effects to date — exhaustion, nausea (but no vomiting), minor bone pain (probably from the Neulasta shot that I get following each chemo infusion), heat flashes and extreme constipation the first week of each cycle, followed by the sense that I am gradually climbing out of a hole. All up I can say THANK God I have my AC rounds. I’m constipated. I was a basket case going in for that shot and I too was put in my place. I am still tired a lot and have to take naps and I’m not sure if thats normal or not. is often given as a combination of drugs. I am not convinced. Typically, it is given after combination Adriamycin (doxorubicin), an anthracycline, and Cytoxan (cyclophosphamide) therapy. I will have a few weeks between the Taxol and radiation. AAAS is a partner of HINARI, AGORA, OARE, CHORUS, CLOCKSS, CrossRef and COUNTER. How did you manage them? Also, constipation is a problem with all the anti-nausea medicine they give. I felt like I had a bad hangover 24/7. While in Florida, one night I woke up with extreme pain in my hip, for which I took Iboprufen and 20 minutes later it was gone. I had my first treatment of taxol yesterday 4/20 and right now I just feel tired but no nausea. Now I know why I don’t do drugs. and was living my old, ignorant but pain-free life. It had hidden in her spine for 17 years, because no one used iodide contrast in her scans. 2017, CT scan without contrast, clean bill of health. Love and light to you all! HER2-positivebreast cancer 3. By the way, I started losing my hair the day after Christmas — the day I started my second cycle with A/C — and counted myself fortunate that I was able to have hair for the Christmas holiday. They all tell me the next medicine isn’t as bad. Chemotherapy may be given by mouth, injection or infusion or on the skin, ... It’s sometimes referred to as the ‘Red Devil’ because it’s a red-colored solution,” he says. © 2020 American Association for the Advancement of Science. 1, 2020 , 1:20 PM. And friends and family have been very supportive. My endocrinologist increased my diabetes medications. I'm Melissa and I'm a 11 yr. You can read of my woes of the Red Devil in my previous post. I have been snowboarding twice and started a clogging class yesterday. The compounds worked as well as the original drug, if not better, at killing cultured cancer cells and were nearly as effective at slowing tumor growth in mice. Just rocking it bald no wig because it seems the treatment has thrown me into menopause. So bad that the only think that kind of helps is a Norco, but I only take it at night just so I’m not loopy all day. Xmas 2018, back ache, CT scan WITH contrast, more than 70 tumors show up, all up and down her spine. The second half of the process was a treatment affectionately known as the “red devil” among cancer bloggers. I was given advice to get the Sancuso patch to help avoid nausea. Chemotherapy is a powerful treatment that involves taking medications to damage cancerous cells. The team now plans to test two potentially safer versions of doxorubicin’s drug class in people. On the 4 treatment, no longer had to take medication! I also attend a weekly therapy group for women with Cancer at the Hospital where I am being treated. Family don’t care what you look like – they just want you there! I used to exercise everyday and drink green smoothies and practice yoga. I just really needed to vent my TRUE feelings. The last dose on 06/5/19 has brought on a type of nausea (hard to explain how it feels) some minor bone, muscle pain but mostly can’t walk far without being out of breath. Isolated from cultures of Streptomyces peucetius var. My hair came back in white like chick feathers and then turned curly salt and pepper look. I was diagnosed with triple negative on April 3, 2018. I have taken the meds for it only occasionally. Brand name: Taxol Chemical name: Paclitaxel Class: Taxane chemotherapy.Abraxane and Taxotere are other taxanes.. How it works: Taxanes interfere with the ability of cancer cells to divide. Can the red devil be defanged? After my second treatment with AC, I was much more careful about what I ate and drank. I would like to get out and at least do 10k steps a day but I’m so exhausted until 2 days before my next treatment. Melissa Paskvan I have tried to do my normal activities, which include exercising. It’s funny how we are all so different. That takes 12 days after chemo to feel decent enough, just in time for the next dose. Chemotherapy can affect your ability to have children, whether you're a man or woman. I did feel like I had the flu ALL the time but when I starte on the taxol I didn’t think I would make it. Any one experience a splitting headache, after first ACT dense dose treatment for breast cancer? It was very difficult to get through. Intravenous route (Solution) Anaphylaxis and severe hypersensitivity reactions characterized by dyspnea and hypotension requiring treatment, angioedema, and generalized urticaria have occurred in clinical trials. After only 3 treatments my Doctor stopped it as it was giving me neuropathy. I did take Zantac regularly, as well as Miralax, and I occasionally took the Ondansetron for nausea. OMG I am not looking forward to that after reading all the comments made. The red devil was easier on me, made me a little sick but easily controlled with meds. Have to be on cymbalta because the tingling in my hands and feet is really bad but that medicine has changed my personality. It’s been about 20 hrs since I was poisoned and I can say I’m doing a bit better. Doxorubicin, known as the red devil for its color and toxicity, is widely used for adult and childhood cancers. This site does not provide medical advice, diagnosis, or treatment. I'm so glad it only lasted 2 days! I have now completed five taxol infusions – my sixth out of 12 is tomorrow. Sleeping through the night is not an option any more. I did 33 treatments of radiation which made me more tired than the chemo. We would like to show you a description here but the site won’t allow us. I know I react different to situations but can’t seem to stop myself. I had Chemo treatments (2½ hour sessions) every other week for 16 weeks,with three visits to the hospital for blood work, Chemo, then I go back the following day to get a shot of Neulasta to bring my white blood cell back up. I was ready for the 4th treatment to be just as bad or worse but the only thing that was worse was my fatigue. I can’t tell you how much it helps to read other people’s battles and realize “I’m normal”. It causes complete hair loss, excessive nausea, fatigue….you name it. Joy Whitlock will never forget the “red devil.” As the red chemotherapy drug pulsed through her body, it became clear to Whitlock how Adriamycin got its nickname. My onc informed me it’s easier than AC. I am still on femara. I had my third round of AC yesterday. My wife had a slight allergic reaction to dose #1 within the first 2 minutes of treatment, was treated with iv Benadryl, steroids and infused the rest of the "red devil" slowly and no subsequent issues. The AC chemo was Hell for me; it was followed by the Neulasta shot and I also took phenergan and Zofran on a regular basis for a few days afterwards so I’m not sure which one gave me these side effects: EXTREME fatigue, sleepiness, aching like I had the worst flu ever, constipation (from the Zofran I think). Thank you all for your comments, I feel that I am not alone. Speak to your physician because they also had prescribed me Zofran, which I was told once I got the patch cannot be taken together. The steriods are in preparation to avoid a reaction, if I don’t react I don’t have to do them again. . Whitlock would try to eat, but it would come right back up. I had to find that inner strength in me again to just do it, focus on 1 day at a time Sleep was my best friend. I always have water on hand – I don’t leave home without it. Combinations usually work I just want to rid myself of this invasive ductal triple negative cancer! I would ask your Doc about the 72 hour infusion, perhaps you can get a bag thing around your waist and take it home. It is used for breast cancer in the early stages as well as for metastatic breast cancer. When I started the Taxol I was told it should be a breeze because I had done so well with the AC. Going out a found s lovely soft angora hat – $35.00 – less than what I paid for the cancer hat. This third one has kicked my butt. My scalp became sore and tingled as I started losing hair about 3 days after my 2nd chemo treatment, going from shedding to rapidly falling out in clumps just by running my fingers through my hair. The work, from an academic team in the Netherlands, upends conventional thinking about doxorubicin and related drugs, suggesting they do not need to directly damage DNA to kill cancer cells. The main thing to remember is that it will not be forever! The side effects, nausea, extreme fatigue, loss of appetite and dry mouth were the worst I experienced. The Taxol kicked my behind. stay the course. Click here to refresh now I'll be getting taxol/herceptin once a week, while I had ac every 3 weeks. However, I started having TERRIBLE night sweats and occasional hot flashes about a month ago. Well, you can forget that. Doxorubicin, an old chemotherapy drug that carries this unusual moniker because of its distinctive hue and fearsome toxicity, remains a key treatment for many cancer patients. Hi….my name is Sharon. Support from family, friends and neighbors, and nea. Taxol is an especially versatile drug. The days after chemo were hellish. Some days, it is all I can do to crawl up my driveway to begin the walk and I fall into bed when I get home again, but I have found multiple benefits from doing this: I’m keeping my muscle tone, doing something that gives me control over my rebellious body, and getting fresh air and sunshine — the world’s best emotional pick-me-ups. I must say, this has been a breeze. EVERY STAGE has challenges. But the scientists have found little corporate interest, and El-Khamisy is skeptical of their plan to develop the drugs on their own. As it turns out spinal cancer is common among BC survivors, since the spine shares blood flow with breasts. We've collected the most helpful community resources to help you prepare for the side effects and coping tips for your chemotherapy regimen. Day 8 after first treatment I fainted while trying to get ready to go for my blood tests, which we then postponed one day. Besides breast cancer and ovarian cancer, Taxol can be used to treat several other types of cancer, including lung cancer and Kap… Doxorubicin is classified as an anthracycline, and it is used to treat breast cancer, bladder cancer, some leukemias, multiple myeloma, ovarian cancer and uterine cancer, among others (chemocare.com) 1. I did great after the first two infusions followed by the Neulasta shot that I gave myself. The pain in my legs and hips was so severe I couldn’t stand up and lived on pain medication. I have a real “following” on Facebook and feel like I can’t disappoint my “fans.” I’m ready to tell the docs, my family, and my dear, dear husband to screw the next A/C and all the rest of the Taxol. Triple Negative Breast Cancer Survivor, I’m ON taxol now. The group has a large grant from the Dutch Cancer Society to start a clinical trial next year of aclarubicin in relapsed leukemia patients. Patient Engagement Portal v.6.0 | Hot flashes made me rip that wig off. I was in the hospital overnight, given tests, had other tests ordered, and was put on anti-seizure medication. I even went back to church. The first couple of treatments were easy but as they accumulated my joints started hurting. I have to take Frmara as well as the chemo. Please enable this “We are doing what usually pharma is doing,” Neefjes says. I agree – the 3rd threw me for a six. © 2021 Navigating Care, Inc. I am 71 years old, am energetic, and a positive attitude, I think it helps! .it is about SAVING MY LIFE and I realize that I can handle all of it. I feel weak, pitiful and just drained from the A/C and I’m scared it won’t get better my doctor says I should feel better in a few weeks. Do not use Taxol without telling your doctor if you are pregnant. YOU CAN DO IT! So we start as. I did feel like I had the flu ALL the time but when I starte on the taxol I didn’t think I would make it. Sharon. I was diagnosed 4 months ago when I was 41, had bilateral mastectomy with 14 lymph nodes removed between the two sides. The red devil was easier on me, made me a little sick but easily controlled with meds. But the researchers found doxorubicin also kills cancer cells by dislodging histones, the spherical proteins that DNA coils around like a spool to form a structure known as chromatin. I noticed a lump in my right breast and had an ultrasound (because I was “too young” for a mammogram, and biopsy on my 29th birthday and received the results a week after. It is often used together with other chemotherapy agents. We will get through this even when we just don’t. Early-stage or node-positive breast cancer 2. JavaScript is disabled in your web browser! Fatal reactions have occurred in patients despite premedication, and all patients should be pretreated with corticosteroids, diphenhydramine, and H2 antagonists. In the new work, the Leiden team tested two anthracycline variants that remove histones without breaking DNA: an approved cancer drug called aclarubicin, and a tweaked version of doxorubicin they call diMe-Doxo. There were times when she didn't have the energy to leave her bed. Hi. Many other chemotherapy agents cause peripheral neuropathy and ice chips or local cryotherapy have been shown to reduce neuropathic symptoms,” said Saria. I know it takes a few days for the side effects to really kick in but I’m scared I’m going to be so tired from weekly infusions hat I won’t. Researchers have tried to reduce the heart risks by, for example, packaging the drugs in fat so they will home in on tumors, with limited success. So hoping for a … BUT giving up is not an option, and with the support from my amazing husband, family and friends, I will push on!!! I went to Florida 3 days after the 1st treatment. Have for the most part gone off tea / coffee. We are all survivors!!! For guys, the reason has to do with the way chemo drugs target fast-growing cancer cells. “This idea was floating around in the literature for many years, but [until now] it has not been proven experimentally,” says Sherif El-Khamisy, who studies DNA repair at the University of Sheffield. Start now! I have cried more in the last two days than I have since my diagnosis two months ago. I was Stage 2B when I started treatment with a tumor 4 1/2 cm in size. I’ve been able to walk up to 2 miles on a great day (I didn’t even consider walking an exercise before), and then I’m exhau. Yet mice prone to developing tumors that were dosed with aclarubicin did not show signs of heart damage, suggesting people treated with the drugs might be spared these effects. I have continued to work since first treatment back in March, only missing the day of chemotherapy. She had a double laminectomy and radiation, but she still died in my arms 30 May, 2019. I do taxol twice a month (it’s a double dose because my oncologist is 1.5 hrs away). I still have neuropathy, but its … Heads up … But I was able to swim in the pool for a couple of times during the week there. To stay logged in, please refresh the page or, if you are working (By the way, when I have mentioned the walking to my doctor, she encourages me; medical studies are showing that gentle exercise like walking is one of the best ways of dealing with chemo side effects.) Even an occasional e-mail or text from an acquaintance is greatly appreciated. caesius (soil fungus), doxorubicin is semi-synthetically produced and is indicated for the treatment of a multitude of cancers, including breast and ovarian, leukemia (acute myelogenous leukemia [AML] and acute lymphoblastic leukemia), Hodgkin lymphoma, … The docs told me that this type of chemo was cumulative and I think I can feel the fatigue building. effects from experts. I went through 5 cycles of the red devil and 10 taxol. If I got through – you can too!!!! No one promised that this would be easy, so if you think of yourself as a warrior in battle, you can be victorious! This is something that I normally would do with my husband. Really! After my first treatment with AC, I followed the advice of what to have when nauseous: fruit juice, including prune juice and other things, all of which just raised my blood sugars even more, once going over 400. Women who got Taxol or Taxotere once a week instead of every 3 weeks seemed to have less severe side effects from the chemotherapy. The Chemo had thrown me into early menopause with hot flashes and night sweats. The only med I took during the 12 week period was nausea meds. They also prescribed the mouth wash (horrible aftertaste) and carafate that increases the saliva production (be ready for stomach lurching) My tongue feels all cut up and I have mouth sores that get better little by little. Jocelyn is a staff writer for Science magazine. Then right before the next dose I have a day or two that I feel ok. I have 3 more double treatments for Triple Neg. Sorry to be such a Debbie Downer. Pending. I know some other meds are given that way. AC followed by Taxol They have antibiotic properties but also proved to be some of the most potent chemotherapies ever found; anthracyclines are used to treat 1 million cancer patients each year, particularly those with leukemia and breast cancer. It also put me into menopause; I am 50 so I was right on the edge anyway. Praying at night has also been helpful. Have moments of feeling hot – hat off – and the cold – hat on. I found sipping water frequently helped immensely with nausea and keeping things moving. What information would you like to pass on to patients who are beginning this medication? I was going to be the breast cancer patient that held up through this like a champion. I know what it’s like to get the “red devil” in the veins. Important Information. In addition, the dexamethasone given with the treatments also raise blood sugar levels. Side effects for two days included exhaustion beyond sleepiness, nausea and depression. Opted for neo-adjuvant chemo in the hopes of saving my breast. I never made to the 3 years mark though. You will survive…. Four hours after the infusion I felt an overwhelming need to lie down and sleep. I’m still trying to work full time so that I can get a check when I have to be out at length for surgery. Thank you. options and managing side Taxol has not been any issue thus far. My Adriamycin and Cytoxan chemo regimen consisted of an infusion once every 21 days. The A/C has been so rough on my body and each dose has gotten harder I was about ready to throw in the towel after the 3rd dose on all of this. I went back last Friday for my 8th treatment and my joints are already hurting again… I only have 4 more to go… Hoping they go by quickly…. I am a basket case. And the 4th – ankles are no where to be found – heart is pumping like a machine that is working overtime, severe headache – my first 1 in 12 weeks. . :(. Connect with thousands of members with your diagnosis and learn from their experiences. Did a mastectomy on my husband and I kept my hair came back white. Paid for the chemotherapy day I rested, and H2 antagonists may due... Managing side effects from the red devil infusions I had planned before the diagnoses a breeze vs Stage 1 they... Make these widely used drugs less toxic.” of AC followed by the Neulasta shot that I will starting. The breast cancer my Stage II diagnosis body heal itself - well up until 12 weeks ago regimen. And drugs from the chemotherapy helped me a lot and have to Frmara! Just how effective these treatments are t stand up and down my is... Half the standard dose cold – hat off – and the neurologist took me off that medication scream outrage... 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