Journal of Hazardous Materials 2005 , 118 (1-3) , 19-34. If allergy (1959)]. OLYMPIC SIZE. Wear protective gloves. Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. Other Effects Ethylene Oxide may cause a skin allergy. Immediately Dangerous to Life or Health Concentrations (IDLH) CAS number: 75–21–8. Ethylene Oxide may damage the testes (male reproductive glands). EtO is both flammable and highly reactive. The Ethylene Oxide Awareness for General Industry safety course from ClickSafety offers introductory-level knowledge regarding this hazardous chemical and all applicable OSHA standards. It has been determined to be carcinogenic to humans. M aterial Safety Data Sheet Issue Date: Aug. 01, 2013 ETHYLENE OXIDE Supercedes: Sep. 01, 2011 Page 2 of 12 GHS Category table for reference: Study/hazard statement Category 1 Category 2 Category 3 Category 4 Category 5 Multiple studies have shown that EO increases the risk of several types of cancer. Most ethylene oxide is used up in the factories where it is produced. Alternative chemicals or processes have, in themselves, serious limitations or health hazards. Provides references that aid in recognizing and evaluating ethylene oxide hazards in the workplace. Provides assistance and information about the management of occupational exposures to ethylene oxide. EtO is both flammable and highly reactive. Emergency Life-Support Procedures: Acute exposure to ethylene oxide may require decontamination and life support for the victims. Ethylene Oxide may damage the developing fetus. Companies that make and work with ethylene oxide are actively investing in research and cutting-edge product stewardship technologies so that we can continue to help protect the health of our communities. (2) • Dermal or ocular contact with solutions of ethylene oxide has caused irritation of the skin and eyes in humans. (2) • Dermal or ocular contact with solutions of ethylene oxide has caused irritation of the skin and eyes in humans. Reproductive Hazard Ethylene Oxide may be a TERATOGEN in humans since it There is limited evidence that Ethylene Oxide causes spontaneous abortions. ONE. Store below 130ºF Use only stainless steel or nickel. Recommended use and restrictions on use. Ethylene oxide is produced in large volumes and is used to make other chemicals, especially ethylene glycol, a chemical used to make antifreeze and polyester. Ethylene Oxide may damage the testes (male reproductive glands). Chronic exposure has been associated with the occurrence of cancer, reproductive effects, mutagenic changes, neurotoxicity, and sensitization. Workers may be harmed from exposure to ethylene oxide. NIOSH REL: <0.1 ppm (<0.18 mg/m 3) TWA, 5 ppm (9 mg/m 3) CEILING, 10-minutes/day; NIOSH considers ethylene oxide to be a potential occupational carcinogen as defined by the OSHA carcinogen policy [29 CFR 1990]. IDENTIFICATION Ethylene is a colorless gas at room temperature. EWG’s Skin Deep rates thousands of personal care product ingredients, culled from ingredient labels on products, based on hazard information pulled from the scientific literature and industry, academic and regulatory databases. Avoid breathing gas. Participants can expect to focus on the properties, primary use of Ethylene Oxide, routes of … What are fire hazards and extinguishing media for ethylene oxide? If allergy Soc. Ethylene Oxide Health and fire hazards of ethylene oxide How you can be exposed to ethylene oxide How we control The Ethylene Oxide Panel supports policies based on the best available science and research on health, safety and environmental issues arising from the production, use, storage, transportation and disposal of ethylene oxide. Exposure to ethylene oxide may cause headache, nausea, vomiting, diarrhea, breathing difficulty, drowsiness, weakness, exhaustion, eye and skin burns, frostbite, and reproductive effects. SWIMMING POOL..1. Any potential association between ethylene oxide and cancer is linked only to chronic exposure. What are fire hazards and extinguishing media for ethylene oxide? Ethylene oxide may severely irritate or burn mucous membranes and moist skin. Environmental Protection Agency (EPA). 1.9 . Ethylene oxide can cause a wide variety of harmful health effects in exposed persons. Eng. TWENTY. IDENTIFICATION OF THE SUBSTANCE OR MIXTURE AND OF THE SUPPLIER 1.1. Ethylene oxide is isomeric with acetaldehyde and with vinyl alcohol. It dissolves easily in water, alcohol, and most organic solvents. Ethylene oxide, called oxirane by IUPAC, is an organic compound with the formula C 2H 4O. GHS Hazard Statements: H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H331 (100%): Toxic if inhaled [Danger Acute toxicity, inhalation]H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] NIOSH recognizes, therefore, that the continued use of ETO as a gaseous sterilant is high … Drying ethylene oxide with magnesium perchlorate resulted in an explosion, [NSC Newsletter, Chem. Unfortunately, EtO possesses several physical and health hazards that merit special attention. The EPA classified the chemical as a human carcinogen in 2016. Ethylene Oxide SAFETY DATA SHEET Effective Date: 10-1-2013 Revision: C ARC Language: EN Page 1 of 17 1. Ethylene Oxide. Note: ADAF -- EPA has concluded that ethylene oxide is carcinogenic by a mutagenic mode of action. It is also used as a fumigant in certain agricultural products and as a sterilant for medical equipment and supplies. Acute exposures to EtO gas may result in respiratory irritation and lung injury, headache, nausea, vomiting, diarrhea, shortness of breath, and cyanosis. Other Effects Ethylene Oxide may cause a skin allergy. Ethylene oxide is industrially produce… Ethylene oxide (C₂H₄O) is a flammable gas with a somewhat sweet odor. The first study to establish a potential link between ethylene oxide and cancer was published in 1948, and in it, researchers found that ethylene oxide is a mutagen. Ethylene oxide is generally synthesized by chlorohydrine process and direct oxidation of ethylene with air, catalyzed by silver(Ag). Flammable Properties: EXTREMELY FLAMMABLE GAS. • Acute inhalation exposure of workers to high levels of ethylene oxide has resulted in nausea, vomiting, neurological disorders, bronchitis, pulmonary edema, and emphysema. GHS product identifier. Acute exposures to EtO gas may result in respiratory irritation and lung injury, headache, nausea, vomiting, diarrhea, shortness of breath, and cyanosis. Wear protective clothing. OLYMPIC SIZE. 1.9 . ONE. Explosions occur , although infrequently, from the combination of ethylene oxide and alcohols or mercaptans, [Chem. TWENTY. * Exposure to Ethylene can cause headache, dizziness, fatigue, lightheadedness, confusion and unconsciousness. Signal word Danger. At very low SWIMMING POOLS. Earth-ground and bond all lines and equipment associated with the system. Ethylene oxide monitoring data from July through October 2019 show little change over the previous nine months. There is minimal cancer risk for the general population because most people are not exposed to significant quantities of ethylene oxide. Ethylene oxide (ETO) is used extensively within health care facilities for sterilization of equipment and supplies. Provides links and references to additional resources related to exposures to ethylene oxide. Congress classified it as a “hazardous air pollutant,” according to the United States Environmental Protection Agency. • Acute inhalation exposure of workers to high levels of ethylene oxide has resulted in nausea, vomiting, neurological disorders, bronchitis, pulmonary edema, and emphysema. Emergency Life-Support Procedures: Acute exposure to ethylene oxide may require decontamination and life support for the victims. Safety Information Ethylene Oxide Exposure. Exposures to ethylene oxide are addressed in specific OSHA standards for general industry, maritime, and construction. At the same time, it … Safety Information. SWIMMING POOL..1. Oxirane 1.2. At 70ºF (21ºC) a nitrogen pressure of 32.6 psig (225 kPa) is required. Unfortunately, EtO possesses several physical and health hazards that merit special attention. The EPA classified the chemical as a human carcinogen in 2016. News 20:1318(1942)]. Ethylene Oxide. Since ethylene oxide hydrolyzes to ethylene glycol which is readily biodegraded, the importance of biodegradation of ethylene oxide in the environment is … Citing the Environmental Protection Agency (EPA) and the Centers for Disease Control and Prevention (CDC), the Washington Department of Labor & Industries cautions health care employers and others who sterilize respirators for reuse that ethylene oxide is a carcinogen that “has been linked to neurologic dysfunction and may cause other harmful effects” to the eyes, […] May 1994. Ethylene Oxide Other means of identification. Ethylene oxide stored in the liquid state can be maintained free of explosion hazard in the gaseous phase by the introduction of nitrogen at sufficient pressure. Provides references that aid in preventing and controlling exposures to ethylene oxide. Ensure that fire extinguishers are available. Ethylene oxide was first discovered more than 160 years ago and signs of health risks from exposure to the gas date back 70 years. Notice to Interested Parties Proposition 65 Listed Chemicals Affected by Hazard Communications Standard Amendments; Notice of Intent to Change the Basis for Listing as Known to the State of California To Cause Reproductive Toxicity: 1,2-Dibromo-3-Chloropropane, Ethylene Oxide and Lead CAS number: 75–21–8 NIOSH REL: <0.1 ppm (<0.18 mg/m 3) TWA, 5 ppm (9 mg/m 3) CEILING, 10-minutes/day; NIOSH considers ethylene oxide to be a potential occupational carcinogen as defined by the OSHA carcinogen policy [29 CFR 1990]. Application of age-dependent adjustment factors (ADAFs) to the inhalation unit risk is recommended in combination with appropriate exposure data … Ethylene Oxide Section 2. Current OSHA PEL: 1 ppm TWA, 5 ppm 15-minute “EXCURSION” 1989 OSHA PEL: Same as current PEL 1993-1994 ACGIH TLV: 1 ppm (1.8 mg/m 3) TWA, A2 Application Ethylene oxide can be used as a precursor to synthesize: ... Safety & Documentation. * Skin contact with liquid Ethylene can cause frostbite. SWIMMING POOLS. Flammable Properties: EXTREMELY FLAMMABLE GAS. Occupational Safety & Health Administration, Occupational Safety and Health Administration, Ethylene Oxide (EtO): Evidence of Carcinogenicity, Special Occupational Hazard Review With Control Recommendations: Use of Ethylene Oxide as a Sterilant in Medical Facilities, International Agency for Research on Cancer (IARC) Monographs on the Evaluation of Carcinogenic Risks for Humans: Ethylene Oxide, International Chemical Safety Cards (ICSC), Severe Storm and Flood Recovery Assistance. Because it is a strained ring, ethylene oxide easily participates in a number of addition reactions that result in ring-opening. Occupational Safety & Health Administration, Occupational Safety and Health Administration, Maximize Your Spirometry Screening and Surveillance Resources, Protect Yourself - Spirometry Breathing Test, OSHA's Small Business Guide for Ethylene Oxide, Severe Storm and Flood Recovery Assistance. ETHYLENE OXIDE IN THE HUMAN BODY. Provides a summary source of information of all potential and most … Protecting the health and safety of the public is a top priority for the producers and users of ethylene oxide and our industry. Symbol GHS02,GHS04,GHS05,GHS06,GHS08. Wear eye or face protection. ETHYLENE OXIDE IN THE HUMAN BODY. No smoking. As a part of the chemical industry’s responsible management of its products, the Ethylene Oxide Panel Ethylene Oxide Safety Task Group (STG), a group comprised of producers and industrial users, developed the Ethylene Oxide Product Stewardship Manual – 3rd edition. Explosive decomposition of ethylene oxide at elevated condition: effect of ignition energy, nitrogen dilution, and turbulence. The following references aid in recognizing and evaluating ethylene oxide hazards in the workplace. Safety data sheet Ethylene Oxide Creation date : 28.01.2005 Version : 2.0 DE / E SDS No. Multiple studies have shown that EO increases the risk of several types of cancer. Lists ethylene oxide as a Hazardous Air Pollutant (HAP) under the National Emissions Standard Hazardous Air Pollutants section of its Clean Air Act. OLYMPIC SIZE. Eye contact may result in conjunctivitis (red, inflamed eyes) and erosion of the cornea. Use only outdoors or in a well-ventilated area. Recommended: Chemical intermediate for production of Ethylene oxide (also known as ETO or oxirane) is a flammable gas with a somewhat sweet odor. Ethylene oxide (EO) is an environmental pollutant and is toxic to humans. Ethylene oxide may severely irritate or burn mucous membranes and moist skin. It is a cyclic ether and the simplest epoxide: a three-membered ring consisting of one oxygen atom and two carbon atoms. Ethylene Oxide may damage the developing fetus. Eye contact may result in conjunctivitis (red, inflamed eyes) and erosion of the cornea. Ethylene oxide is not an acute health hazard but can be harmful if continually ingested over time. Many workers are unaware of the potential hazards in their work environment, which makes them more vulnerable to injury. History of Ethylene Oxide . Ethylene oxide (EO) is an environmental pollutant and is toxic to humans. UN 1040 Ethylene Oxide UN 1040 Ethylene Oxide Labels 2.3, 2.1 Hazard number 263 Packing Instruction P200 IMDG Class 2.3 UN number and proper shipping name UN 1040 Ethylene Oxide Labels 2.3, 2.1 Packing Instruction P200 EmS FD,SU IATA Class 2.3 UN number and proper shipping name UN 1040 Ethylene Oxide Labels 2.3, 2.1 Hazards identification Prevention :Obtain special instructions before use. In general, with higher levels of exposure to the chemical, more severe effects will occur. Ethylene oxide is a colorless and flammable gas with a faintly sweet odor. Ethylene oxide is one of 187 hazardous air pollutants or “air toxics” that EPA regulates under the Clean Air Act. Ethylene oxide decomposes or polymer… OLYMPIC SIZE. Ethylene oxide. New Jersey Department of Health and Senior Services, Hazardous Substance Fact Sheet, (Revised November 2009). View 301 Chapter 6 MSDS EtOKit.ppt from CHEMICAL 434 at Universiti Teknologi Mara. Hazard statements (GHS-US) : H220 - EXTREMELY FLAMMABLE GAS H280 - CONTAINS GAS UNDER PRESSURE; MAY EXPLODE IF HEATED H315+H320 - CAUSES SKIN AND EYE IRRITATION It dissolves easily in water.Ethylene oxide is a man-made chemical that is used primarily to make ethylene glycol (a chemical used to make antifreeze and polyester). Reproductive Hazard Ethylene Oxide may be a TERATOGEN in humans since it There is limited evidence that Ethylene Oxide causes spontaneous abortions. Ethylene oxide is a flammable gas with a somewhat sweet odor. * Ethylene is a HIGHLY FLAMMABLE and REACTIVE chemical and a DANGEROUS FIRE and EXPLOSION HAZARD. Ethylene oxide is expected to volatilize from dry soil surfaces (SRC) based upon a vapor pressure of 1.31X10+3 mm Hg (4). Ethylene oxide (EtO) is produced in large volumes and is primarily used as an intermediate in the production of several industrial chemicals, the most notable of which is ethylene glycol. The Ethylene Oxide Panel supports policies based on the best available science and research on health, safety and environmental issues arising from the production, use, storage, transportation and disposal of ethylene oxide. All electrical equipment should be non-sparking or explosion proof. 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